I got the chance to play with a Boeing 747 flight simulator quite a few times.   I was leading a project for the machine control and propulsion systems for frigates and had to go to the subcontractor's machine room simulator.  Lucky for me, I had a friend who was working on the Boeing 747 simulators just next door.

The first time I tried to land was with the simulator set for Hong Kong airport.  I oversteered (it's really easy to do the first time) and everyone else in the cockpit got really sick to their stomach.  My friend was co-piloting and we were on ILS but bounced off the runway before landing.  Just steering the bloody thing to the terminal is difficult, and I am drive a manual transmission Jeep

They have devices to simulate motion in the cabin and the seats, and even the cabin smells the same.  When I opened the door, I was sure that I had taken a trip somewhere because the smell of the hydraulic oil reminded me so much of taking a trip.

It was great fun, and it took me at least 6 weeks to get used to handling the controls.