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IIRC, two Albuquerque hidalgos sailed from Portugal around 1500 and defeated the Mameluke navy, seizing control of the Red Sea and thereby increasing the price of spices which they shipped around Africa.  

"It is not necessary to have hope in order to persevere."
by ARGeezer (ARGeezer a in a circle eurotrib daught com) on Fri Dec 30th, 2011 at 09:17:54 AM EST
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